Pain killer Tetracaine Hydrochloride Local Anesthetic Tetracaine HCl with Safe Shipping

Tetracaine HCl
Tetracaine HCl Alias: Tetracaine hydrochloride ,2-Dimethylaminoethyl 4-n-butylaminobenzoate hydrochloride; Amethocaine hydrochloride
Tetracaine HCl CAS : 136-47-0
Tetracaine HCl Molecular formula: C15H25ClN2O2
Tetracaine HCl Molecular weight: 300.82
Tetracaine HCl EINECS: 205-248-5
Appearance: Fine white crystalline and odorless powder
Melting point: 145~150 degree
Assay: 99%
Grade: Pharmaceutical Grade
Usage: Local anesthetic; Mainly used in mucosa anesthetic. The function is stronger than Procaine and Lidocaine.Tetracaine HCl

What is Tetracaine Hydrochloride?

Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.

Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5‱ (per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.

It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.

A systematic review and meta-analysis of randomised controlled trials investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties – however it did not find a statistically significant improvement in first attempt

Topical Pain Relief Powders Tetracaine Hydrochloride Application :

Tetracaine (INN, also known as amethocaine; trade name Pontocaine. Ametop and Dicaine) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia.

In biomedical research, tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely.

Tetracaine HCl Dosage:

1. For tonometry and other short procedures: Instill 1 to 2 drops in the eye(s) just prior to evaluation.

2. For minor surgical procedures, such as foreign body or suture removal: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 1 to 3 instillations.

3. For prolonged anesthesia, such as cataract extraction: Instill 1 to 2 drops in the eye(s) every 5 to 10 minutes for 3 to 5 doses

940f.jpg

 

Advertisements

Procaine Hcl Pharmaceutical Raw Material Procaine Hydrochloride Procaine Powder

Aminocaine; Anadolor; Anesthesol; Anestil; Atoxicocaine; Benzoicacid, 4-amino-, 2-(diethylamino)ethylester, monohydrochloride; Benzoicacid, p-amino-, 2-(diethylamino)ethylester, monohydrochloride; Bernocaine

CAS No.: 51-05-8
EINECS: 200-077-2
MF: C13H21ClN2O2
MW: 272.771
Melting point: 155-156 ° C(lit. )
Boiling point: 195-196° C 17mm
Flashing point: 195-196° C/17mm
Solubility in water: Soluble
Sensitivity: Air Sensitive
Stability: Stable. Incompatible with strong oxidizing agents.
Function:
Local anesthetics. Mainly for infiltration anaesthesia, spinal anesthesia and conduction anesthesia. It is not suitable for surface anesthesia.

Procaine Hydrochloride Application:

Procaine HCl is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, in some regions procaine is referred to generically  It acts mainly by being a sodium channel blocker.Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.

Procaine HCl is indicated for the production of local or regional analgesia and anesthesia by local infiltration and peripheral nerve block techniques.

Application of procaine leads to the depression of neuronal activity. The depression causes the nervous system to become hypersensitive producing restlessness and shaking, leading to minor to severe convulsions. Studies on animals have shown the use of procaine led to the increase of dopamine and serotonin levels in the brain.Other issues may occur because of varying individual tolerance to procaine dosage. Nervousness and dizziness can arise from the excitation of the central nervous system, which may lead to respiratory failure if overdosed. Procaine may also induce weakening of the myocardium leading to cardiac arrest.

Procaine can also cause allergic reactions causing the individuals to have problems with breathing, rashes, and swelling. Allergic reactions to procaine are usually not in response to procaine itself, but to its metabolite PABA. About one in 3000 people have an atypical form of pseudocholinesterase,[citation needed] which does not hydrolyze ester anesthetics such as procaine, resulting in a prolonged period of high levels of the anesthetic in the blood and increased toxicity.

pl15798781-medication_grade_local_anesthetic_powder_procaine_hcl_powder_cas_51_05_8.jpg

 

Prilocaine / Prilocaine Hcl 99% Pure Raw Powder on Sale

Pharmacology

Stabilizes the neuronal membrane by inhibiting the ionic fluxes needed for the initiation and conduction of impulses, thereby affecting local anesthetic action.

Indications and Usage

Production of local anesthesia in dentistry by nerve block or infiltration techniques.

Contraindications

Hypersensitivity to amide-type local anesthetics; patients with congenital or idiopathic methemoglobinemia.

Dosage and Administration

Adults

Infiltration For most routine procedures, initial doses of 1 to 2 mL will provide adequate infiltration or major nerve block anesthesia. Maximum recommended dose is 8 mg/kg (4 mg/lb) in patients weighing less than 70 kg (150 lb) and 600 mg in patients weighing 70 kg (150 lb) or more.

Children younger than 10 yr of age

Infiltration Seldom necessary to administer doses greater than 40 mg for a procedure involving a single tooth.

Storage/Stability

Store at 77°F. Protect from light.

99% Pharmaceutical Grade Lidocaine / Lidocaine Hcl Local Anesthetic —-Safe Delivery to UK

 

Product Name Lidocaine Hydrochloride
Other Name 2-(Diethylamino)-N-(2,6-dimethylphenyl) acetamide hydrochloride
Assay (%) ≥99.5 Odor Characteristic
Color White crystalline powder Cas No. 73-78-9
Molecular Formula C14H23ClN2O Molecular Weight 270.7982
Standard BP2007/USP31
Function Main functions are as follows:
1.Local anesthetic.
2. Treating Epilepsy.
3. Treating Asthma.
Applications Main applications are as follows:
Applied in pharmaceuticalfields.
Packing 1kgor 5kg/bag,  25kg/drum
Shelf Life 24 months
Storage Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.

lidocaine-hydrochloride.jpg

Benzocaine / Benzocaine Hcl Local Anesthetic Drug

Benzocaine is a local anesthetic drug. It is directly applied to the skin and used as a topical pain reliever or in cough drops. Benzocaine works by creating a chemical barrier that halts the build up of sodium, which accumulates as the nerve endings are stimulated by pain. When sodium builds up, electrical signals also build in the nerve ending and are transmitted to the brain, which interprets the signals as pain. Benzocaine hydrochloride is a salt modification of benzocaine, formed when benzocaine is complexed with hydrochloric acid. Compared to benzocaine, benzocaine hydrochloride is more water soluble, making it more appropriate for oral administration.

Benzocaine hydrochloride is usually made into powder or oil paste and used to heal wounds, ulcers, burns, skin abrasion, and hemorrhoids. Through the reduction in the excretion of ammonia and carbon dioxide of fish by benzocaine hydrochloride, the pH and alkalinity values of the transport water remains constant, thereby, benzocaine hydrochloride is used as an aid in the transport of fish.

相关图片