Molar mass:1311.5 g/mol
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH).
Triptorelin is used to treat prostate cancer
Triptorelin dosing information
Usual Adult Dose for Prostate Cancer:
Due to different release characteristics, the dosage strengths are not additive and must be selected based upon the desired dosing schedule.
3.75 mg intramuscularly (IM) every 4 weeks
or11.25 mg IM every 12 weeks
or22.5 mg IM every 24 weeks
Comments: Administered as a single intramuscular injection in either buttock.
Use: Palliative treatment of advanced prostate cancer